XSEED was recently asked about the possibility of localizing Rune Factory IV. The company previously brought Rune Factory Frontier to North America.
Responding to the question on its Facebook page, XSEED wrote:
“Hmmm, we’ve had an itch to work on another Rune Factory game since we loved Frontier so much, so let’s see if we can’t grab a back scratcher somehow…”
If XSEED doesn’t release Rune Factory IV in the states, maybe Natsume can. Other than that, I’m not sure about any other companies that would get involved.